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Compound Aminopyrine Antipyrine Barbitone Injection

March 30,2023


This product is a compound preparation, and its components are: 0.1g of aminopyrine, 0.04g of antipyrine, and 0.018g of barbital per 2ml.

Auxiliary materials: disodium edetate, water for injection.


This product is a colorless or yellowish clear liquid.


As a generic drug supplier in China, Feiyue Pharmaceutical can provide finished drugs such as Compound Aminopyrine Antipyrine Barbitone Injection

Packaging: 10 pieces/box

FEIYUE recruits agents worldwide, we can provide complete registration documents.


It is mainly used for emergency antipyretic treatment during acute high fever, and also has a relieving effect on headache symptoms during fever.

Usage and dosage:

Intramuscular injection.

Adults should take 2ml (1 tablet) at a time, or follow medical advice. Under monitoring, the maximum amount is 6 ml per day (3 capsules per day).

Children under 2 years of age: 0.5-1 ml once (1/4-12 tubes once); 2-5 years old: 1-2 ml once (1/2 to 1 dose once); Over 5 years of age: 2ml (1 dose) once.

This product is not suitable for continuous use.

Adverse reactions:

"Anaphylactic shock, characterized by chest tightness, dizziness, nausea, vomiting, decreased blood pressure, sweating, and other symptoms, should be immediately discontinued and rescued.".

2. Granulocyte deficiency, purpura, and sometimes acute onset.

3. Rashes, urticaria, epidermal lysis, etc.


It is prohibited for those who are allergic to pyrazolone or barbiturates, and those who have a history of allergy to this product.

matters needing attention:

Before intramuscular injection, the patient should be asked if they have a history of allergy to pyrazolone or barbiturates. Those with a history of allergy should avoid using this product, and those with allergic constitution should also use it with caution.

2. Do not mix injection with other drugs.

Long term use can cause severe toxic reactions such as granulocytopenia, aplastic anemia, and liver and kidney damage.

4. Use this product with caution if you have serious respiratory diseases or breathing difficulties.

5. Use with caution if you are weak.

6. This product is only for symptomatic treatment. After relieving the symptoms of high fever, it should be treated accordingly. If the application of this product has no obvious effect, it should be treated with other methods to avoid blindly using this product in large quantities.

7. It is strictly prohibited to use in food and feed processing.


Drug interactions:

Barbital has an inhibitory effect on the respiratory center and has a strengthening effect on drugs that can inhibit respiration, such as gentamicin sulfate, and should not be used simultaneously.

Pharmacology and toxicology:

This product is an antipyretic and analgesic drug. Aminopyrine and antipyrine are both pyrazolone antipyretics and analgesics, which can inhibit the synthesis and release of prostaglandins in the hypothalamus, restore the normal reactivity of temperature regulating central sensory neurons, and play an antipyretic role; It also has an analgesic effect by inhibiting the synthesis of prostaglandins, etc. Aminopyrine can also inhibit the synthesis and release of prostaglandins in local inflammatory tissues, stabilize the lysosomal membrane, and affect the phagocytosis of phagocytes, thereby playing an anti-inflammatory role. Combined use of barbital can enhance the analgesic effect.


Protect from light and store tightly.