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Scopolamine Butylbromide Injection

November 23,2022


The main ingredient of this product is scopolamine butylbromide . Chemical name: 6β,7β- epoxy -3α- hydroxy -8- butyl -1αH,5αH- tropine (-)-palmitate bromide

Molecular formula: C 21H 30BrNO 4 Molecular weight: 440.38. Auxiliary materials are sodium chloride and water for injection.


This product is colorless or almost colorless clear liquid.

As a generic drug supplier in China, Feiyue Pharmaceutical can provide finished drugs such as Scopolamine Butylbromide Injection

Packaging: 1ml:10mg 1ml:20mg

FEIYUE recruits agents worldwide, we can provide complete registration documents.


1. For acute gastrointestinal tract, biliary tract and urinary tract spasm, including biliary colic and renal colic; 2. Assist in the diagnosis or treatment of spasticity, such as gastroscopy and imaging examination.


This product is administered by intramuscular injection and slow intravenous injection. At present, it is recommended for adults to take 10 ~ 12mg each time, or 10mg at a time, and then 10mg at intervals of 20 ~ 30min. This product is recommended as a short-term symptomatic treatment. No reduction is required for patients with renal failure or liver failure.

adverse effect

The following frequency of adverse reactions of this product is based on the data collected from clinical trials. Presumably, the incidence of adverse reactions that have not been observed in clinical trials, but have been reported during post-marketing use is less than 0.1% (rare). The following table describes the incidence of adverse reactions according to the representation method of CIOMS, namely: very common (≥10%), common (1% ~ 10%, including 1%), occasional (0.1% ~ 1%, including 0.1%) and rare (0.01% ~ 0.1%, including). Http:// Adverse reactions such as headache, nausea, vomiting and dry mouth can also be reported in this product, but the incidence rate is still unclear.


1. It is forbidden for patients who are known to be allergic to the active ingredients or any other ingredients of this product. 2. This product is forbidden in the following situations: untreated angle-closure glaucoma, prostatic hypertrophy with urinary retention, mechanical stricture of gastrointestinal tract, tachycardia, megacolon and myasthenia gravis.

drug interaction

1. The toxicity of this product will increase when contracted with other anticholinergic drugs and phenothiazines. 2. This product can antagonize the gastrointestinal motility of metoclopramide, domperidone and other drugs. 3. Some antiarrhythmic drugs (such as quinidine, propitiamide, etc.) should be used with caution. Because the former can block the vagus nerve, it can enhance the anticholinergic effect of this product, leading to dry mouth, blurred vision and dysuria. The elderly should pay special attention to it. 4. The combination of this product with adrenergic drugs (e.g. dextroamphetamine 5mg) can enhance the anti-vomiting effect and reduce the drowsiness effect of this product, but the dry mouth is more obvious. 5. When this product is combined with tricyclic antidepressants (amitriptyline, etc.), because both of them have anticholinergic effects, it can enhance the adverse reactions such as dry mouth, constipation, blurred vision, etc., causing urinary retention in elderly patients, inducing acute glaucoma and paralytic intestinal obstruction, etc., so it is forbidden to combine these two drugs. 6. When this product is combined with digoxin, nitrofurantoin, vitamin B2, etc., it will obviously enhance the absorption of the latter. 7. During the application of this product or other anticholinergic drugs, when sublingual nitroglycerin is used to prevent or treat angina pectoris, the latter's disintegration is slowed down due to the decrease of saliva, thus affecting its absorption, and its effect may be delayed and/or weakened.


Symptoms: Anticholinergic effects can be observed when overdose occurs, such as urinary retention, dry mouth, skin flushing, tachycardia, gastrointestinal peristalsis inhibition and transient visual impairment. Treatment: Parasympathetic drugs can alleviate the symptoms caused by excessive application of scopolamine butylbromide injection. Glaucoma patients should be treated urgently according to ophthalmic recommendations; Treat cardiovascular complications according to general treatment principles; If respiratory paralysis occurs, tracheal intubation and artificial respiration should be considered. Urinary retention may require indwelling catheter. Use appropriate supportive treatment when necessary.

store up

Keep under 30℃ in a light-proof and airtight condition.

matters need attention

1, this product should be discontinued when allergic reaction occurs.

2. When using this product for patients with low blood pressure, attention should be paid to prevent postural hypotension.

3, subcutaneous or intramuscular injection should pay attention to avoid nerves and blood vessels, if you need repeated injection should not be in the same place, should be left and right alternate injection.

4. It is forbidden to be compatible with alkali, iodine and tannic acid.

5. Infants and children should use it with caution.

6. The elderly should exclude the history of heart disease and prostatic hypertrophy before taking medicine.

7. If overdose can cause delirium, agitation, even convulsion, respiratory failure and even death, it can be rescued with cholinergic drugs and other symptomatic treatments.