0.5g, 1.0g Ceftriaxone Sodium ngoba Injection

I-Ceftriaxone isetshenziselwa ukwelapha izifo ezimbi kakhulu ezilandelayo uma zibangelwa izinto ezisengozini (bona Isenzo ukuze uthole uhlu olugcwele):
- ukutheleleka komgudu wokuphefumula ophansi
- izifo zesikhumba nesakhiwo sesikhumba
- izifo zomgudu womchamo, aziyinkimbinkimbi futhi ziyinkimbinkimbi
– i-gonorrhea engaxakile
- ukutheleleka kwegazi nge-bacterial (sepsis)
- izifo zamathambo
- izifo ezihlangene
- meningitis
I-Ceftriaxone ingasetshenziswa futhi ekuvimbeleni ukutheleleka ngesikhathi sokuhlinzwa okufana nokuhlinzwa kwe-vagin noma kwesisu, ukukhishwa kwenyongo, izinqubo zokuhlinza ezingcolile (isb: ukuhlinzwa kwamathumbu) kanye nokuhlinzwa kwe-graft ye-coronary bypass graft.
Njengokwelashwa kwazo zonke izifo, izifundo zesiko nokuzwela kufanele zenziwe ngaphambi kwesikhungo sokwelashwa uma kungenzeka.

Imininingwane

I-Ceftriaxone iyi-antibiotic ye-spectrum ebanzi evela emndenini we-cephalosporin. Iyaziwa njenge-cephalosporin yesizukulwane sesithathu, futhi iyasebenza ngokumelene nenani lamagciwane angabulawa i-cephalosporins yesizukulwane sokuqala noma sesibili. I-Ceftriaxone ibulala amagciwane ngokuphazamisa ukukhiqizwa kwamaprotheni abalulekile ezindongeni zamangqamuzana awo. Isebenza ngokumelene nenani lezinto eziphilayo ezibalulekile futhi ezaziwa kakhulu okuhlanganisa:
I-Staphylococcus aureus (kodwa hhayi i-MRSA)
– E. coli
- Neisseria meningitidis (meningococcus)
– N. gonorrhoeae (isizathu se-gonorrhoea)
I-Ceftriaxone iphinde ibulale ezinye izinto ezibalulekile eziyimbangela yezifo zepheshana lokuphefumula, i-Haemophilus influenzae, i-Streptococcus pneumoniae ne-Klebsiella pneumoniae. Ezinye izinhlobo ze-Pseudomonas aeruginosa, isinambuzane esidala izifo eziyingozi zasesibhedlela, nazo ziyabulawa. Idlanzana lamanye amabhaktheriya abangela izifo eziningi angenwa kalula yi-Ceftriaxone.

I-Rocephin ingase iphathwe nge-intramuscularly noma nge-intramuscularly.
Abantu abadala
- umthamo wansuku zonke onconyiwe ngu-1-2g kanye ngosuku noma ngemithamo ehlukaniswe ngokulinganayo kabili ngosuku
– umthamo unqunywa ngokusekelwe ebucayi bokutheleleka
I-gonorrhea engaxakile
– umthamo owodwa we-IM wama-250mg
I-prophylaxis yokuhlinzwa
Umthamo owodwa we-1g kufanele unikezwe ¨ö emahoreni ama-2 ngaphambi kokuhlinzwa
Izingane
- 50-75mg/kg/ngosuku njengomthamo owodwa noma imithamo ehlukanisiwe
- umthamo ungadluli ku-2g / ngosuku
– umthamo kufanele uhlukaniswe futhi unikezwe njalo emahoreni ayi-12 ku-meningitis
Ubude besikhathi sokwelashwa
- ngokuvamile, ukwelashwa kufanele kuqhutshwe okungenani izinsuku ezimbili ngemva kokunyamalala kwezimpawu zokutheleleka
- ubude besikhathi esijwayelekile yizinsuku ezi-4-14
– ukwelashwa kungase kube isikhathi eside ezifweni ezithile, isb: ukutheleleka ngethambo
- Ukwelashwa isikhathi eside kwandisa ingozi yemiphumela emibi
- izifo ezibangelwa i-Streptococcus pyogenes kufanele zelashwe izinsuku ezingekho ngaphansi kweziyi-10
Ukukhubazeka kwezinso
- Amazinga e-plasma kufanele abhekwe ezigulini ezinokukhubazeka kwe-renal ne-hepatic, kanye neziguli ezinokukhubazeka okukhulu kwezinso.
- amazinga e-serum akufanele adlule i-280mcg/ml
Administration
- zonke izixazululo ezilungiselelwe kufanele zisetshenziswe ngokushesha ngangokunokwenzeka futhi zigcine ukusebenza kwazo amahora ayisithupha ekamelweni lokushisa
Umjovo wemisipha
- ncibilikisa 250mg noma 500mg ku-2ml, noma 1g ku-3.5ml, we-lignocaine 1% isixazululo
- phatha ngomjovo ojulile we-intragluteal
– akufanele kujovwe ngaphezu kwe-1g ohlangothini ngalunye
– umjovo ngaphandle kwe-lignocaine kubuhlungu
– isixazululo se-lignocaine akufanele neze sijovwe ngomjovo
Ukujova ngomjovo
- chaza u-250mg noma 500mg ku-5ml, noma i-1g ku-10ml, wamanzi omjovo
- sebenzisa ngomjovo oqondile emithanjeni imizuzu emi-2-4
Ukumnika ngomjovo
- ncibilikisa u-2g ku-400ml wanoma iluphi uketshezi lwe-IV ONGAqukethe i-calcium
- sebenzisa ngokumnika okungenani imizuzu engama-30

S4

I-Ceftriaxone ngokuvamile ibekezelelwa kahle. Imiphumela elandelayo itholakala ngokujwayelekile:
– isifo sohudo
– isicanucanu
– ukuqubuka
- ukuphazamiseka kwe-electrolyte
- ubuhlungu nokuvuvukala endaweni yomjovo

Imiphumela elandelayo ivela kancane:
– ukuhlanza
– ikhanda
- isiyezi
- i-thrush yomlomo kanye ne-vaginal
- isifo sohudo esinamandla (pseudomembranous colitis)
Ukungezwani komzimba akuvamile kodwa izimpawu zibalulekile ukwazi futhi kufanele zibikwe kudokotela wakho:
– isifuba
– ukulunywa
- ukuvuvukala
– ukuphefumula kanzima
- ukukhala
– ukuqubuka okunsomi okwandile